3-bromo-5-(trifluoromethyl)-benzenemethanol is an organic compound with the chemical formula C8H7BrF3O.
Nature:
3-bromo-5-(trifluoromethyl)-benzenemethanol is a colorless liquid with a distinctive odor. It is an organofluorine compound with a high degree of chemical stability and inertness. It is soluble in organic solvents such as ethanol, dimethyl sulfoxide and dimethylformamide.
Use:
3-bromo-5-(trifluoromethyl)-benzenemethanol is an important organic synthesis intermediate, which is widely used in the manufacturing process of pesticides, fluorescent dyes, pharmaceuticals and flexible display materials. It can also be used in organic synthesis reactions, such as addition reactions, substitution reactions and hydroxyl protection reactions.
Method:
3-bromo-5-(trifluoromethyl)-benzenemethanol can be prepared by reacting benzyl alcohol with trifluoromethylmagnesium bromide. The specific step is to first react benzyl alcohol and trifluoromethylmagnesium bromide to form the corresponding alkyl magnesium bromide, and then react with bromine to form 3-bromo-5-(trifluoromethyl)-benzenemethanol.
The reaction equation is as follows:
Safety Information:
3-bromo-5-(trifluoromethyl)-benzenemethanol is relatively stable at room temperature, but decomposition reaction may occur at high temperature or in the presence of organic hydrogenation agent. It is an organic fluorine compound with certain toxicity. Attention should be paid to protective measures to avoid contact with skin and eyes. Use protective gloves, goggles and protective clothing during operation. If inhaled or ingested by mistake, you should seek medical treatment immediately.